logo

Development, ageing & pathology

The Development, Ageing & Pathology research department is a research cluster of the University Medical Campus Brussels, bringing together researchers from the Faculty of Medicine & Pharmacy at Vrije Universiteit Brussel and from the Universitair Ziekenhuis Brussel. DAP is a research cluster consisting in 7 research departments: INTG, FRIA, GRON, URGE, MIPI, HEEL and ANES.

The research of the department Development, Aging & Pathology fits within the general theme "Development, Ageing and Pathology" with 3 major researchniches:

1) Developmental Aspects,

2) Environmental Aspects, and

3) Degenerative & Age-Related Aspects.

The prioritary researchlines of DAP are mainly linked to the specificity of DAP's research departments.

Events

Calender
Thursday 20 January, 14:00

Multistakeholderism in the European Union’s Trade Policy-Making

Doctoraatsverdediging van Diana Potjomkina voor het behalen van de academische graad van Doctor in de politieke wetenschappen met het proefschrift getiteld ‘Multistakeholderism in the European Union’s Trade Policy-Making’....

Doctoraatsverdediging van Diana Potjomkina voor het behalen van de academische graad van Doctor i...

Thursday 20 January, 17:00

Improving human-robot interaction through empathy and transparency

Public PhD defense in fulfilment of the requirements for the degree of Doctor of Engineering Sciences of Mrs. Elahe Bagheri. Please find attached the invitation.

Public PhD defense in fulfilment of the requirements for the degree of Doctor of Engineering Scie...

Friday 21 January, 12:00

Opleidingsintervisie

In kleine groep (max. 5 deelnemers) wordt tijdens de opleidingsintervisie gestructureerd en onder begeleiding uitgewisseld rond thema's die u zelf aandraagt. U leert met en van collega's rond moeilijkheden die ieder van u dagelijks tegenkomt bij het opleiden op de werkvloer. Open ...

In kleine groep (max. 5 deelnemers) wordt tijdens de opleidingsintervisie gestructureerd en onde...

Saturday 22 January, 14:00

Songing with our Ancestors: Voice Workshop with Johanna Peine and TOI

How much of jellyfish, fish or amphibian is still present in the human body and voice? In this workshop we try to get to the bottom of this question by exploring the movements of early phylo- and ontogenesis in connection with the sound of our voice. According to the phoniatrist J....

How much of jellyfish, fish or amphibian is still present in the human body and voice? In this wo...

Saturday 22 January, 20:00

Songing with our Ancestors: Live Radio Session with Peggy Pierrot

Live radio session with writer, radio dj and educator Peggy Pierrot.

Live radio session with writer, radio dj and educator Peggy Pierrot.

Tuesday 25 January, 20:00

Hydrofeminisms

The ocean holds numerous stories of kinship between the human and the more-than-human. One of those stories tells of the ancient oceanic ancestors of our present-day (human) bodies of water. Traces of many of those ancestors, such as the amoeba or the jellyfish, are still present...

The ocean holds numerous stories of kinship between the human and the more-than-human. One of tho...

ANES

Chairman: prof. dr. Jan Poelaert - jan.poelaert@uzbrussel.be

The department of Anesthesiology and Perioperative Medicine, Acute and Chronic Pain conducts both experimental and clinical studies with respect to pathophysiology of pain, other inflammatory pathways (induced by ischaemia, infarction, surgery, hypothermia) and pharmacokinetic and –dynamic studies of anaesthetics.

 Xenon anaesthesia (severely decreased left ventricular function)

  • Microcirculation
  • Rhythm disturbances and anaesthetics
  • Lung aeration in ventilated patients – outcome of mechanical ventilation techniques
  • Thoracoscopic ablation and postoperative pain
  • Adjuvantia and local anaesthetics – new local anaesthestics
  • AKI and postoperative patients
  • Thoracic epidural analgesia and cardiac function in one- and bilateral lung ventilation
  • Pharmacokinetics and pharmacodynamics of anaesthestics (propofol, sufentanil)

FRIA

Chairman: prof. dr. Ivan Bautmans - ivan.bautmans@vub.ac.be
Second contact: prof. dr. Ingo Beyer – ingo.beyer@uzbrussel.be

The Frailty in Ageing Research department conducts a comprehensive research program to untangle the underlying mechanisms and to develop interventions for prevention and rehabilitation of frailty in the aged.

  • Effect of physical training on immunosenescence (inflammation, senescent cells), sarcopenia (age-related muscle atrophy), dynapenia (age-related muscle weakness) and cognition: Senior PRoject INtensive Training (SPRINT)
  • Effect of inflammation on Sarcopenia and muscle weakness: Intervention with anti-inflammatory products; Role of infections in the elderly; Role of Advanced Glycation End products
  • Identification and characterization of senescent cells: T-lymphocytes; Influence of chemotherapy; Influence of corticoids
  • Motivational aspects of physical exercise and active ageing.
  • Early detection of dementia and mild cognitive impairment

GRON

Chairman: prof. dr Brigitte Velkeniers - brigitte.velkeniers@uzbrussel.be

Contact Endocrinology: prof. dr. Bert Bravenboer– bert.bravenboer@uzbrussel.be

Contact Nefrology: prof. dr. Christian Tielemans - Christian.tielemans@uzbrussel.be

Contact Pneumology: dr. Eef Vanderhelst – eef.vanderhelst@uzbrussel.be

Contact Intensive Medicin: prof. dr. Herbert Spapen – Herbert.spapen@uzbrussel.be

  • Pediatric pneumology: Epidemiology/microbiology in otherwise healthy children (CAP and persistent wheezing, CAP complicated with empyema) and in CF-patients (Biofilm formation, S. aureus, Burkholderia cepacia, respiratory viruses), Immunological response (Pertussis and Tuberculosis), new diagnostics in CF (Nasal potential differentials), new treatments in CF, and pharmacological studies (asthma medication, CF new treatments, evaluation of vaccines), and participation in several multicentric studies (infectiology, CF)

Contact Pneumology: dr. Eef Vanderhelst – eef.vanderhelst@uzbrussel.be

  • Pediatric gastroenterology: Milk allergy, Gastro-oesophageal reflux and Crohn’s disease
  • Pediatric hematology-oncology and immunology : Cooperation in international intervention studies in Childhood cancers, studies concerning supportive care aspects in Childhood cancer, studies in a coagulation disorders, Immunoglobulin substitution therapy phase II trial, cooperation with several international partners for patient based reseach in primairy immunodeficiencies, defects in the innate immune system, management of invasive fungal infections.
  • Deontology & Ethics. Deontological, ethical and legal implications of the care for minors.
  • Pediatric nefrology: The study for "Aliskeren" in pediatric patiënts with hypertension. 

Contact Research Methodology and Rheumatology: prof. dr. Muriel Stubbe -Muriel.Stubbe@uzbrussel.be

  • Neonatology: cooperation in multicentre interventional randomized controlled studies (e.g. SToP-BPD trial), cooperation with international studies on pharmacokinetics and pharmacodynamics of drugs in newborn infants (e.g. Pharmacool study), involvement in the international Cochrane Collaboration (meta-analysis, individual patient data meta-analysis)

HEEL

The department of surgery works in close collaboration with the Diabetes Centre of UZ Brussels

  • Neural influence in the resolution of type 2 diabetes mellitus after Roux-en-Y gastric bypass in patients with morbid obesity
  • Clinical application of beta cells transplantion in type 1 diabetes
  • Nutrition and cancer
  • Research into the neurogenic influence trough the nervus vagus on oxidative stress at the periphery (o.a. adipose tussue) and chronic inflammation in the metabolic syndrome.
  • Lymphedema & breastcancer
  • Gastrointestinal Tumors (GIST): Analysis gene-mutation/ Open versus laparoscopic intervention

MIPI

The Research Group Microbiology and Infection Prevention focuses on diagnosis, epidemiology, treatment and prevention of infectious diseases.

  • Microbiology: Diagnosis, treatment and epidemiology of infectious diseases, especially pertussis, diphtheria, legionellosis, Verotoxin-producing E. coli infections, new bacterial identification techniques,Burkholderia cepacia complex in cystic fibrosis patients, anaerobic infections & antibiotic sensitivity, HIV infection and AIDS, and congenital infections (CMV, toxoplasmosis).
  • Infection Prevention: surveillance and prevention of nosocomial infections

Ear, nose and throat: Hearing loss and congenital CMV infection, sinusitis, assessment of the influence of nasal versus oral breathing on the craniofacial development.

  • ENT-complications due to Fusobacterium necrophorum infections
  • HPV-positive oropharyngeal squamous cell carcinomas

ReGEDiM-URGE

Research Group on Emergency and Disaster Medicine (ReGEDiM-URGE)

 

The Research Group on Emergency and Disaster Medicine conducts a research program focused on different aspects of both emergency and disaster medicine :

  • Emergency Medicine: Training, Quality Assessment and Quality Improvement, Information Technology (IT)-applications, Data-management and Process-analysis, Outcome predictors in emergency medicine, Cardiopulmonary resuscitation, Developments in medical imaging techniques , Patient satisfaction and Patient Information, Geriatric & Pediatric emergency care.
  • Disaster Medicine: Evidence-based Disaster Medicine, Modeling and Simulation of Disasters and Disaster Medical Management, Disaster Medical Management, Disaster Mental Health, Disaster Ethic