Integration of Dynamic Arterial Elastance into Daily Haemodynamic Monitoring
ID: MSCA-19-Poelaert01
Topic
Research Unit of the Department of Anesthesiology and Perioperative Medicine
The Research Unit of the Department of Anesthesiology and Perioperative Medicine performs both research concerning anaesthetics (local or intravenous–related to plasma levels) with departmental funding or company sponsored (phase III or IV trials), as well as haemodynamic studies with monitoring or cardiac ultrasound. Research nurses support this endeavor both from the administrative as well clinical side.
BENE research group (Beta Cell Neogenesis)
The BENE research group (Beta Cell Neogenesis) is fully focused on the study of processes to generate beta cells by proliferation and/or differentiation and has made major contributions to
(i) glucose sensing system in alpha- and beta cells,
(ii) transcription factors that support the phenotype of beta cells and control reprogramming of non-beta cells of the endocrine pancreas,
(iii) development of experimental models to study beta cell neogenesis by differentiation from stem/progenitor cells and by cycling of preexisting and newly formed beta cells.
Studies by BENE were published in 135 research papers in a1, international and peer reviewed, journals.
The research group consists of 13 members (4 postdocs, 5 PhD students, 2 research assistants and 2 technicians).
Epigenetic reprogramming during oogenesis: unravelling the link with oocyte developmental competence and with offspring health.
ID: MSCA-19-Anckaert01
Topic
FOBI Research Group
The FOBI lab investigates the design and validation of new culture systems for ovarian follicles and unripe egg cells.
We therefore aim to establish practical, applicable strategies for fertility clinics.
We conduct fundamental research into in-vitro culture systems for ovarian follicles and egg cells and fundamental mechanistic research into the effects of xenobiotic substances upon in-vitro egg cell development.
We also conduct fundamental and pre-clinical research into in-vitro maturation of unripe egg cells from small antral follicles.
Our clinical activities entail the cryopreservation of gonadal tissue for female patients to avoid sterility, or in other words, preservation of fertility during cancer treatment, and in-vitro maturation (IVM) of oocytes from small follicles.
Investigating and understanding male infertility–the biology of the testis
ID: MSCA-19-GOOSSENS01
Topic
BITE Research Group
The research group BITE has performed pioneering work on in vivo strategies for fertility preservation in young boys needing gonadotoxic treatment (SSC transplantation and tissue grafting). These are now being translated to clinical applications. However, these in vivo strategies will not benefit young boys suffering from systemic or metastasizing cancers (risk for transplanting back malignant cells), patients with Klinefelter syndrome (sclerotic testes at adult age), and patients with non-obstructive azoospermia. These patients might benefit from in vitro strategies.