Understanding and targeting tumor biology
The research group specialized in myeloma biology combines expertise in tumor biology, immunotherapy, epigenetics, cellular metabolism, extracellular vesicles, CAR T cell engineering and cancer genetics to advance the understanding and treatment of Multiple Myeloma. The team of researchers is led by prof. dr. Karin Vanderkerken and part of the Translational Oncology Research Centre (TORC),
By integrating fundamental laboratory research with clinical innovation, we investigate the biological drivers of disease, uncover vulnerabilities in tumor cells, develop next-generation immunotherapies and cell-based treatments, and apply cutting-edge genetic and liquid biopsy technologies to improve diagnosis and patient monitoring. Together, our scientists and clinicians work to translate discoveries into targeted, effective therapies that improve outcomes for patients with Multiple Myeloma and related blood cancers.
Applying novel cellular therapies & liquid biopsies
At UZ Brussel, clinical research focuses on translating innovative cellular therapies and advanced diagnostic tools into improved care for patients with Multiple Myeloma. The hematology team develops and applies next-generation treatments such as CAR-T cells, dendritic cell–based immunotherapies and stem cell transplantation strategies, while also using liquid biopsies and molecular profiling to detect minimal residual disease and track the genetic and epigenetic evolution of the cancer. Supported by internationally recognized JACIE accreditation and national cell bank licenses, the cell therapy program integrates laboratory expertise with clinical experience to deliver safe, effective and personalized therapies to patients.
Our mission
By integrating fundamental biology, immunotherapy development, clinical innovation and genetic diagnostics, our goal is to:
- Detect disease activity earlier and more precisely
- Develop targeted and more effective therapies
- Tackle relapse and therapy-resistant forms of Multiple Myeloma
- Improve survival and quality of life for patients
Donate now and make a difference
Donate online or by bank transfer to the VUB's account number BE51 0013 6779 3562 stating GIFTFD13. Donations from 40 euros are tax deductible.